20 QUESTIONS · 5 TOPICS · GENE TRANSLATOR · ABOUT 15 MINUTES

Change one letter of DNA and a blood cell changes shape.

Sickle-cell disease comes from swapping a single A for a T in the haemoglobin gene, out of about 3 billion letters in your genome. Twenty questions on how DNA becomes protein, each explained, then make that mutation yourself. No sign-up, nothing saved.

Start the test
THE CENTRAL DOGMA
DNAATG GTG CATthe master copy
↓ transcription
mRNAAUG GUG CAUthe working copy
↓ translation
ProteinMet – Val – Hisdoes the work
QUESTION 1 / 20 · DNA & GENESEasy

In DNA, adenine (A) always pairs with…

GENE TRANSLATOR

Mutate a gene, see the protein change

The DNA is copied into mRNA, then read three letters (one codon) at a time to pick each amino acid. Click any DNA base to select it, then swap, insert or delete a base and compare the protein with the original.

DNAmRNAProtein
AUGMet
GUGVal
CAUHis
CUGLeu
ACUThr
CCUPro
GAGGlu
GAGGlu
AAGLys
UCUSer
GCCAla
Base 20 (A): change to
MUTATION TYPENo mutationThis is the start of the human β-globin gene. To make the sickle-cell mutation, select the A in codon 7 (GAG, glutamate) and change it to T, making GTG (valine).
ORIGINAL PROTEINMet–Val–His–Leu–Thr–Pro–Glu–Glu–Lys–Ser–AlaYOURSMet–Val–His–Leu–Thr–Pro–Glu–Glu–Lys–Ser–Ala
HydrophobicPolarPositive chargeNegative chargeGlycineStop

What this molecular biology test covers, in short

Twenty multiple-choice questions at upper-secondary to first-year university level, four on each of five topics: DNA and genes, replication, transcription and translation, mutation, and gene regulation and biotechnology.

The translator uses the standard genetic code and the real opening of the human β-globin gene (HBB). This test is our own and not normed.

By What's Your IQ · Reviewed 5 Oct 2026
Format
20 multiple-choice questions
Level
A-level / AP to first-year
Bonus
DNA → mRNA → protein translator with mutations
Milestone
Double helix, 1953

Keep going

Reading code three letters at a time? That's pattern reasoning.

Our full IQ test covers pattern, logical, numerical and verbal reasoning: 60 questions, about 30 minutes.

Take the full IQ test